Nurse Jackie Season 4 Premiere Photos! Nurse Jackie Peyton returns to Showtime for ten all-new episodes starting Sunday, April 8th at 9pm. B. Alan Orange — March 7, 2012 Facebook Twitter Reddit Flipboard Email Comment Nurse Jackie is set to debut all-new episodes starting April 8th, only on Showtime. Season 4 kicks things off with Episode 4.01: Kettle-Kettle-Black-Black. We have a look at this premiere with eight photos featuring Edie Falco and her cast mates. Check them out.