Mila Kunis, Ashton Kutcher, Laura Prepon and Wilmer Valderrama from That '70s Show reunite on camera to remember their earliest break into stardom and growing up on set; and members of one of Hollywood's most comedic families - Keenen Ivory Wayans, Marlon Wayans and Shawn Wayans - come together to share stories about their funniest sketches on In Living Color during Fox's 25th Anniversary Special, airing Sunday, April 22 (8:00-10:00 PM ET/PT).

The star-studded special will pay tribute to Fox's most memorable moments with appearances by Fox talent, highlights from iconic series and specials and reunions with cast members from some of the network's fan-favorite series, among other surprises.

Also featured in the special are Randy Jackson, Jennifer Lopez, Ryan Seacrest and Steven Tyler from American Idol; Kiefer Sutherland from 24 and Touch; and Seth MacFarlane from Family Guy, The Cleveland Show and American Dad!.

Previously announced participants include Christina Applegate, David Faustino, Ed O'Neill and Katey Sagal who sit down together and salute Married with Children; Calista Flockhart from Ally McBeal; Gabrielle Carteris, Shannen Doherty, Jason Priestley and Ian Ziering from Beverly Hills, 90210; Patrick Warburton from The Tick; and Gillian Anderson, David Duchovny and creator Chris Carter from The X-Files.

The host and additional Fox talent to be announced.

Fox's 25th Anniversary Special is executive-produced by Don Mischer and Charlie Haykel. Juliane Hare will serve as producer and Louis J. Horvitz will direct the special.